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Cytokeratin 18 Mouse Monoclonal Antibody [A4B3]

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Product Specifications

Product Name Alternative

Cell proliferation inducing gene 46 protein antibody Cell proliferation inducing protein 46 antibody Cell proliferation-inducing gene 46 protein antibody CK 18 antibody CK-18 antibody CK18 antibody CYK 18 antibody CYK18 antibody Cytokeratin 18 antibody Cytokeratin endo B antibody Cytokeratin-18 antibody K 18 antibody K18 antibody K1C18_HUMAN antibody KA18 antibody Keratin 18 antibody Keratin 18, type I antibody Keratin D antibody keratin, type I cytoskeletal 18 antibody Keratin-18 antibody Krt18 antibody

Abbreviation

KRT18, CYK18, PIG46

Swiss Prot

P05783 Human, P05784 Mouse, Q5BJY9 Rat

Cellular Locus

Nucleus matrix, Cytoplasm, perinuclear region, Nucleus, nucleolus.

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human Cytokeratin 18 aa 1-150.

Isotype

IgG2a

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, FC, IF-Cell

Positive Control

SK-Br-3 cell lysate, A549 cell lysate, A431 cell lysate, MCF7 cell lysate, mouse liver tissue lysate, rat liver tissue lysate, HeLa, human liver tissue, human skin tissue, human prostate carcinoma tissue, human breast carcinoma tissue, MCF-7.

Concentration

2 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500 ;FC: 1:50-1:100 ;IF-Cell: 1:100

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

CAS Number

9007-83-4

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