Sigma1-receptor Rabbit Polyclonal Antibody
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
SIGMAR1
Swiss Prot
Q99720 Human, O55242 Mouse
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within human Sigma1-receptor aa 74-223.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
293T cell lysate, HepG2 cell lysate, mouse liver tissue lysate, human liver tissue, human placenta tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:600-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 25 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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