TGF beta 1 Rabbit Polyclonal Antibody
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Transforming growth factor beta-1 proprotein Latency-associated peptide LAP Transforming growth factor beta-1 TGF-beta-1 TGFB1 TGFB
Swiss Prot
P01137 Human
Cellular Locus
Extracellular matrix, Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human TGF beta 1 aa 20-210.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
PC-3 cell lysate, A549 cell lysate, U87 cell lysate, Hela cell lysate, K562 cell lysate.
Concentration
1 mg/mL
Dilution
WB:1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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