GABRA6 Rabbit Polyclonal Antibody
Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. One study has found a genetic variant in the gene to be associated with the personality trait neuroticism.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Gamma-aminobutyric acid receptor subunit alpha-6, GABA (A) receptor subunit alpha-6, GABAAR subunit alpha-6, GABRA6
Swiss Prot
Q16445 Human, P16305 Mouse, P30191 Rat
Cellular Locus
Postsynaptic cell membrane, Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human GABRA6 aa 43-242 / 453.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Jurkat cell lysate, PC-3 cell lysate, rat testis tissue lysates, rat testis tissue, rat brain tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
51 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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