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SKP2 Rabbit Polyclonal Antibody

S-phase kinase-associated protein 2 is an enzyme that in humans is encoded by the SKP2 gene. Skp2 contains 424 residues in total with the ~40 amino acid F-box domain lying closer to the N-terminal region at the 94-140 position and the C-terminal region forming a concave surface consisting of ten leucine-rich repeats (LRRs). The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which often—but not always—recognize substrates in a phosphorylation-dependent manner. In this SCF complex, Skp2 acts as the substrate recognition factor.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

CDK2/Cyclin A associated protein p45 antibody Cyclin A/CDK2 associated protein p45 antibody Cyclin-A/CDK2-associated protein p45 antibody F box protein Skp2 antibody F box/LRR repeat protein 1 antibody F-box protein Skp2 antibody F-box/LRR-repeat protein 1 antibody FBL 1 antibody FBL1 antibody FBXL 1 antibody FBXL1 antibody FLB 1 antibody FLB1 antibody MGC1366 antibody p45 antibody p45skp2 antibody S phase kinase associated protein 2 (p45) antibody S phase kinase associated protein 2 antibody S-phase kinase-associated protein 2 antibody S-phase kinase-associated protein 2 E3 ubiquitin protein ligase antibody SKP 2 antibody Skp2 antibody SKP2_HUMAN antibody

Abbreviation

SKP2

Swiss Prot

Q13309 Human

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human SKP2 aa 1-150 / 424.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

Siha cell lysate, HepG2 cell lysate, 293T cell lysate, HeLa, human placenta tissue.

Concentration

1.783 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:400 ;IF-Cell: 1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 46/48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

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