PLCB3 Rabbit Polyclonal Antibody
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 is an enzyme that in humans is encoded by the PLCB3 gene. The gene codes for the enzyme phospholipase C β3. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11, as well as G-beta gamma subunits. PLCB3 has been shown to interact with Sodium-hydrogen exchange regulatory cofactor 2.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Phosphoinositide phospholipase C-beta-3 Phospholipase C-beta-3 PLC-beta-3 PLCB3
Swiss Prot
Q01970 Human, Q9NQ66 Human, P51432 Mouse, Q9Z1B3 Mouse, P10687 Rat, Q99JE6 Rat
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human aa 2-251.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Concentration
2.06 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:600
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 139 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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