PPP2R1B Rabbit Polyclonal Antibody
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform is an enzyme that in humans is encoded by the PPP2R1B gene. This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Swiss Prot
P30154 Human, Q7TNP2 Mouse, Q4QQT4 Rat
Cellular Locus
Secreted, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human PPP2R1B aa 100-350.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Concentration
2.4 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:600 ;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 66 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![S100 beta (S100B) Mouse Monoclonal Antibody [Clone ID: OTI3G6]](https://cdn.genprice.uk/products/937/68dd18b9061270361e90802f/imageurl/cf807235.webp)
S100 beta (S100B) Mouse Monoclonal Antibody [Clone ID: OTI3G6]
![PIN4 Mouse Monoclonal Antibody [Clone ID: OTI7H2]](https://cdn.genprice.uk/products/937/68dd18ba061270361e908429/imageurl/cf808412.webp)
