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Gab2 Rabbit Polyclonal Antibody

Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

GAB 2 antibody Gab2 antibody GAB2_HUMAN antibody Grb 2 associated binder 2 antibody GRB 2 associated binding protein 2 antibody Grb2 associated binder 2 antibody GRB2 associated binder 2 pp100 antibody GRB2 associated binding protein 2 antibody GRB2-associated binder 2 antibody GRB2-associated-binding protein 2 antibody Growth factor receptor bound protein 2 associated protein 2 antibody Growth factor receptor bound protein 2-associated protein 2 antibody KIAA0571 antibody p97 antibody PH domain containing adaptor molecule p97 antibody pp100 antibody

Abbreviation

GRB2-associated-binding protein 2 GRB2-associated binder 2 Growth factor receptor bound protein 2-associated protein 2 pp100

Swiss Prot

Q9UQC2 Human, Q9Z1S8 Mouse, Q9EQH1 Rat

Cellular Locus

Cell membrane, Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human Gab2 aa 450-676 / 676.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

Hela cell lysate, mouse brain tissue lysate, rat brain tissue lysates, SHSY5Y cell lysates, rat kidney tissue, human throid gland tissue, human esophagus tissue, A549, SH-SY5Y.

Concentration

1 mg/mL

Dilution

WB:1:500-1:2,000;IHC-P:1:100-1:400;IF-Cell: 1:50-1:100;FC: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

74 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Curated Selection

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