Gab2 Rabbit Polyclonal Antibody
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
GRB2-associated-binding protein 2 GRB2-associated binder 2 Growth factor receptor bound protein 2-associated protein 2 pp100
Swiss Prot
Q9UQC2 Human, Q9Z1S8 Mouse, Q9EQH1 Rat
Cellular Locus
Cell membrane, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human Gab2 aa 450-676 / 676.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000;IHC-P:1:100-1:400;IF-Cell: 1:50-1:100;FC: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
74 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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