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HNF1 alpha Rabbit Polyclonal Antibody

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Albumin proximal factor antibody Hepatic nuclear factor 1 alpha antibody Hepatic nuclear factor 1 antibody Hepatic transcription factor 1 alpha antibody Hepatic transcription factor 1 antibody Hepatocyte nuclear factor 1-alpha antibody HNF 1 antibody HNF 1A antibody HNF-1-alpha antibody HNF-1A antibody hnf1a antibody HNF1A_HUMAN antibody Interferon production regulator factor antibody LF B1 antibody LF B1 hepatic nuclear factor antibody LFB 1 antibody LFB1 antibody LFB1 hepatic nuclear factor antibody Liver specific transcription factor LF B1 antibody Liver specific transcription factor LFB1 antibody Liver-specific transcription factor LF-B1 antibody Maturity onset diabetes of the young 3 antibody MODY 3 antibody MODY3 antibody TCF 1 antibody TCF-1 antibody TCF1 antibody Transcription factor 1 antibody Transcription factor 1 hepatic antibody

Abbreviation

HNF1A

Swiss Prot

P20823 Human, P22361 Mouse, P15257 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human HNF1 alpha aa 100-300 / 631.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

HepG2 cell lysate, mouse uterus tissue lysate, human kidney tissue lysate, rat kidney tissue, human small intestine tissue, mouse liver tissue, HepG2.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IHC-P: 1:100-1:500 ;FC: 1:500-1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

67 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Curated Selection

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