Lck Rabbit Polyclonal Antibody
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
LCK
Swiss Prot
P06239 Human, Q01621 Rat
Cellular Locus
Cytosol, Cell membrane.
Host
Rabbit
Species Reactivity
Human,Rat
Immunogen
Recombinant protein within human Lck aa 100-300 / 509.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
Rat thymus tissue lysate, Jurkat cell lysate, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
58 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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