Mitoferrin1 Rabbit Polyclonal Antibody
SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009). Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe (2+), is then probably delivered to ferrochelatase to catalyze Fe (2+) incorporation into protoprophyrin IX to make heme (By similarity).
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
SLC25A37
Swiss Prot
Q9NYZ2 Human, Q920G8 Mouse
Cellular Locus
Mitochondrion inner membrane.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within human Mitoferrin1 aa 289-338.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Mouse spleen tissue lysates, mouse brain tissue lysate, THP-1 cell lysate, Hela, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50;IHC-P: 1:400
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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