TMEM119 Rabbit Polyclonal Antibody
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
OBIF antibody Osteoblast induction factor antibody PSEC0199 antibody Transmembrane protein 119 antibody UNQ731/PRO1415 antibody
Abbreviation
OBIF TMEM119 PSEC0199 UNQ731/PRO1415
Swiss Prot
Q4V9L6 Human, Q8R138 Mouse
Cellular Locus
Endoplasmic reticulum membrane, Cell membrane, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within human TMEM119 aa 11-52 / 283.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
Mouse brain tissue lysate, mouse hippocampus tissue lysate, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;IF-Cell: 1:50-1:100 ;FC: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 29 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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