SNRPD3 Rabbit Polyclonal Antibody
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity).
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Small nuclear ribonucleoprotein Sm D3 Sm-D3 snRNP core protein D3 SNRPD3
Swiss Prot
P62318 Human, P62320 Mouse
Cellular Locus
cytosol, Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within C-terminal human SNRPD3.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Jurkat cell lysate, mouse lung tissue lysate, MCF-7 cell lysates, human colorectal carcinoma tissue, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB:1:500;IHC-P:1:100-1:400
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
14 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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