p53R2 Rabbit Polyclonal Antibody

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

DKFZp686M05248 antibody MGC102856 antibody MGC42116 antibody MTDPS8A antibody MTDPS8B antibody p53 inducible ribonucleotide reductase small subunit 2 homolog antibody p53 inducible ribonucleotide reductase small subunit 2 like protein antibody P53 inducible ribonucleotide reductase small subunit 2 short form beta antibody p53 R2 antibody p53-inducible ribonucleotide reductase small subunit 2-like protein antibody p53R2 antibody Ribonucleoside diphosphate reductase M2 subunit B antibody Ribonucleoside-diphosphate reductase subunit M2 B antibody Ribonucleotide reductase M2 B (TP53 inducible) antibody Ribonucleotide reductase M2 B antibody Ribonucleotide reductase small subunit like 2 p53 inducible antibody RIR2B_HUMAN antibody RRM 2B antibody RRM2B antibody TP53 inducible ribonucleotide reductase M2 B antibody TP53-inducible ribonucleotide reductase M2 B antibody

Abbreviation

RRM2B

Swiss Prot

Q7LG56 Human, Q6PEE3 Mouse,

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within C-terminal human p53R2 from aa 200-aa351.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

Rat skeletal muscle tissue lysate, mouse skeletal muscle tissue lysate, mouse cerebellum tissue lysate, human skeletal muscle tissue lysate, Daudi cell lysate, mouse colon tissue, rat cerebellum tissue, SH-SY5Y.