CLCNKB Rabbit Polyclonal Antibody
The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CLCNKB
Swiss Prot
P51801 Human, Q9WUB6 Mouse, P51802 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within C-terminal human CLCNKB from aa520-aa687.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Mouse testis tissue lysate, rat testis tissue lysate, MCF-7 cell lysate, human kidney tissue, human seminoma tissue, MG-63, A549, A431, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:100-1:500;IF-Cell: 1:50-1:100;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
75 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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