NDE1 Rabbit Polyclonal Antibody
Selected Variant
HA500198
Size: 100 µL
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
NDE1
Swiss Prot
Q9NXR1 Human, Q9ES39 Rat
Cellular Locus
Cytoskeleton, centrosome, spindle, kinetochore, cleavage furrow.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human NDE1 aa 1-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Rat brain tissue lysates, rat cerebellum tissue, human liver tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:100-1:500 ;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
38 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Price
Frequently Asked Questions
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