CYP24A1 Rabbit Polyclonal Antibody
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1, CYP24
Swiss Prot
Q07973 Human, Q64441 Mouse, Q09128 Rat
Cellular Locus
Mitochondrion.
Host
Rabbit
Species Reactivity
Mouse,Rat,Human
Immunogen
Recombinant protein within human aa 50-250.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat bladder tissue lysates, mouse lung tissue lysates, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:10,000 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
59 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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