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Hexokinase II Rabbit Polyclonal Antibody

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

DKFZp686M1669 antibody Hexokinase 2 antibody Hexokinase 2 muscle antibody Hexokinase type II antibody Hexokinase-2 antibody HK 2 antibody HK II antibody HK2 antibody HKII antibody HxK 2 antibody HxK2 antibody HXK2_HUMAN antibody Muscle form hexokinase antibody

Abbreviation

HK2

Swiss Prot

P52789 Human, O08528 Mouse, P27881 Rat

Cellular Locus

Cytosol, Mitochondrion outer membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human Hexokinase II aa 1-200.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

293 cell lysate, Jurkat cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, rat skeletal muscle tissue lysate, SiHa, rat testis tissue, human fetal skeletal muscle tissue, mouse kidney tissue, Hela, PC-12.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:100-1:500 ;FC: 1:500-1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 102 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

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