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CCR3 Rabbit Polyclonal Antibody

Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES (CCL5) and CCL15 . Subsequently transduces a signal by increasing the intracellular calcium ions level . In addition acts as a possible functional receptor for NARS1 . (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. Overexpression of CCR3 together with its ligands appears to be a characteristic of ulcerative colitis (UC). The production of CCR3 ligands by human colonic epithelial cells suggests further that the epithelium can play a role in modulating pathological T-cell-mediated mucosal inflammation.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

B chemokine receptor antibody b-chemokine receptor antibody C C chemokine receptor type 3 antibody C C CKR 3 antibody C-C chemokine receptor type 3 antibody C-C CKR-3 antibody CC chemokine receptor 3 antibody CC chemokine receptor type 3 antibody CC CKR 3 antibody CC R3 antibody CC-CKR-3 antibody CCCKR3 antibody CCR 3 antibody CCR-3 antibody CCR3 antibody CCR3_HUMAN antibody CD 193 antibody CD193 antibody CD193 antigen antibody Chemokine (C C motif) receptor 3 antibody chemokine (C-C motif) receptor 3 antibody Chemokine (CC) receptor 1 like 2 antibody Chemokine CC motif receptor 3 antibody Chemokine receptor 3 antibody CK R3 antibody CKR 3 antibody CKR3 antibody CMKB R3 antibody CMKBR 3 antibody CMKBR1L2 antibody CMKBR3 antibody Eosinophil CC chemokine receptor 3 antibody Eosinophil eotaxin receptor antibody Eotaxin receptor antibody Macrophage inflammatory protein 1 alpha receptor like 2 antibody MGC102841 antibody MIP1 Alpha RL2 antibody

Abbreviation

C-C chemokine receptor type 3 C C CKR3 C-C CKR-3 CC-CKR-3 CCR-3 CCR3 CKR 3 CKR3 Eosinophil eotaxin receptor CD193

Swiss Prot

P51677 Human, P51678 Mouse, O54814 Rat

Cellular Locus

Cell membrane, Membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within C-termina human CCR3.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB

Positive Control

Rat lung tissue lysate, human liver tissue lysate, mouse liver tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 43 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Frequently Asked Questions

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