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ASIC4 Rabbit Polyclonal Antibody

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Acid-sensing ion channel 4 ASIC4 Amiloride-sensitive cation channel 4 Amiloride-sensitive cation channel 4, pituitary ACCN4

Abbreviation

ASIC4

Swiss Prot

Q96FT7 Human, Q7TNS7 Mouse, Q9JHS6 Rat

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human ASIC4 aa 250-450.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

HepG2 cell lysate, human brain tissue lysate, K562 cell lysate, rat brain tissue, mouse pituitary tissue, SH-SY5Y.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IHC-P: 1:100-1:500 ;FC: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

70 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

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