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Phospho-AKT2 (S474) Rabbit Polyclonal Antibody

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Akt2 antibody AKT2_HUMAN antibody HIHGHH antibody Murine thymoma viral (v-akt) homolog 2 antibody murine thymoma viral (v-akt) homolog-2 antibody Oncogene AKT2 protein kinase B beta antibody PKB antibody PKB beta antibody PKBB antibody PKBBETA antibody PRKBB antibody Protein kinase Akt 2 antibody Protein kinase Akt-2 antibody Protein kinase B beta antibody RAC beta antibody rac protein kinase beta antibody RAC-BETA antibody RAC-beta serine/threonine-protein kinase antibody RAC-PK-beta antibody RACbeta antibody v akt murine thymoma viral oncogene homolog 2 antibody V-AKT murine thymoma viral oncogene homolog 2 antibody

Abbreviation

AKT2

Swiss Prot

P31751 Human, Q60823 Mouse

Cellular Locus

Cell membrane, Nucleus, Early endosome, Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide within human AKT2 aa 450-481 (phospho S474).

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

Hela treated with Calyculin A whole cell lysate, Hela treated with insulin whole cell lysate, human kidney tissue, mouse testis tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

56 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Frequently Asked Questions

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