GXYLT1 Rabbit Polyclonal Antibody
Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. GXYLT1 is a xylosyltransferase (EC 2.4.2.-) that adds the first xylose to O-glucose-modified residues in the epidermal growth factor (EGF; MIM 131530) repeats of proteins such as NOTCH1. GXYLT1 (Glucoside Xylosyltransferase 1) is a Protein Coding gene. Diseases associated with GXYLT1 include Dowling-Degos Disease and Adams-Oliver Syndrome. Among its related pathways are Mucin type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring glycosyl groups and UDP-xylosyltransferase activity. An important paralog of this gene is GXYLT2.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Glycosyltransferase 8 domain-containing protein 3 antibody Glucoside xylosyltransferase 1 antibody GXYLT1 antibody GLT8D3 antibody
Abbreviation
Glycosyltransferase 8 domain-containing protein 3 Glucoside xylosyltransferase 1 GXYLT1 GLT8D3
Swiss Prot
Q4G148 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human GXYLT1 aa 400-440.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
U937 cell lysate, HL-60 cell lysate, HUVEC cell lysate, human fetal skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 51 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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