NR3B Rabbit Polyclonal Antibody
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
GRIN3B
Swiss Prot
O60391 Human
Cellular Locus
Cell membrane, postsynaptic cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human NR3B aa 179-220 (Extracellular domain).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
THP-1 cell lysate, 293 cell lysate, Daudi cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
113 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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