NR3B Rabbit Polyclonal Antibody
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia.
Product Specifications
Product Name Alternative
Abbreviation
GRIN3B
Swiss Prot
O60391 Human
Cellular Locus
Cell membrane, postsynaptic cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human NR3B aa 179-220 (Extracellular domain).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
THP-1 cell lysate, 293 cell lysate, Daudi cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
113 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
CAS Number
9007-83-4
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