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MEOX2 Rabbit Polyclonal Antibody

Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

GAX antibody Growth arrest-specific homeobox antibody Homeobox protein MOX 2 antibody Homeobox protein MOX-2 antibody meox2 antibody MEOX2_HUMAN antibody Mesenchyme homeobox 2 antibody MOX2 antibody

Abbreviation

Homeobox protein MOX-2 Growth arrest-specific homeobox Mesenchyme homeobox 2

Swiss Prot

P50222 Human, P39020 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Rat

Immunogen

Synthetic peptide within human MEOX2 aa 255-304/304.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

Rat kidney tissue lysates, rat kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500;IHC-P: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

34 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

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