OTC/Ornithine Carbamoyltransferase Rabbit Polyclonal Antibody
Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme (EC 2.1.3.3) that catalyzes the reaction between carbamoyl phosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (Pi). There are two classes of OTC anabolic and catabolic. This article focuses on anabolic OTC. Anabolic OTC facilitates the sixth step in the biosynthesis of the amino acid arginine in prokaryotes.[5] In contrast, mammalian OTC plays an essential role in the urea cycle whose purpose is to capture toxic ammonia and transform it into less toxic urea nitrogen source for excretion.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Ornithine carbamoyltransferase, mitochondrial (EC:2.1.3.3) Ornithine transcarbamylase OTCase
Swiss Prot
P00480 Human, P11725 Mouse, P00481 Rat
Cellular Locus
Mitochondrion.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human OTC/Ornithine Carbamoyltransferase aa 200-354.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Rat colon tissue lysate, human liver tissue lysate, mouse liver tissue lysate, SW480, human liver carcinoma tissue, human liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
40 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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