Complement factor B Rabbit Polyclonal Antibody
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
C3/C5 convertase antibody Complement factor B antibody Glycine-rich beta glycoprotein antibody PBF2 antibody Properdin factor B antibody
Abbreviation
Swiss Prot
P00751 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human,Rat
Immunogen
Recombinant protein within human Complement factor B aa 20-230.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Rat liver tissue lysates, SKOV-3, human liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 86 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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