CIRP Recombinant Rabbit Monoclonal Antibody [JE55-46]

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'- UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

A18 hnRNP antibody A18HNRNP antibody cirbp antibody CIRBP_HUMAN antibody CIRP antibody Cold inducible RNA binding protein antibody Cold-inducible RNA-binding protein antibody Glycine rich RNA binding protein antibody Glycine-rich RNA-binding protein CIRP antibody testicular tissue protein Li 39 antibody

Abbreviation

CIRBP

Swiss Prot

Q14011 Human

Cellular Locus

Nucleoplasm, Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant full length protein of Human CIRP.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Raji cell lysate, Hela cell lysate, Daudi cell lysate, human thyroid tissue, human colon carcinoma tissue, human prostate carcinoma tissue, human kidney tissue, human pancreas tissue.