P4HB Recombinant Rabbit Monoclonal Antibody [JE54-98]

This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Cellular thyroid hormone binding protein antibody Cellular thyroid hormone-binding protein antibody Collagen prolyl 4 hydroxylase beta antibody Disulphide Isomerase antibody DSI antibody EC 5.3.4.1 antibody Endoplasmic reticulum resident protein 59 antibody ER protein 59 antibody ERBA2L antibody ERp59 antibody GIT antibody Gltathione insulin transhydrogenase antibody Glutathione insulin transhydrogenase antibody P4HB antibody P4Hbeta antibody p55 antibody PDI antibody PDIA1 antibody PDIA1_HUMAN antibody PDIR antibody PHDB antibody PO4DB antibody PO4HB antibody Procollagen proline 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase) beta polypeptide (protein disulfide isomerase associated 1) antibody Procollagen proline 2 oxoglutarate 4 dioxygenase beta subunit antibody PROHB antibody Prolyl 4 hydroxylase beta polypeptide antibody Prolyl 4 hydroxylase beta subunit antibody Prolyl 4 hydroxylase subunit beta antibody Prolyl 4-hydroxylase subunit beta antibody Protein disulfide isomerase associated 1 antibody Protein disulfide isomerase, family A, member 1 antibody Protein disulfide isomerase/oxidoreductase antibody Protein disulfide-isomerase antibody Protocollagen hydroxylase antibody Thbp antibody Thyroid hormone binding protein p55 antibody Thyroid hormone binding protein p55 cellular antibody V erb a avian erythroblastic leukemia viral oncogene homolog 2 like antibody

Abbreviation

P4HB

Swiss Prot

P07237 Human, P09103 Mouse, P04785 Rat

Cellular Locus

Endoplasmic reticulum, endoplasmic reticulum lumen, cell membrane, melanosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human P4HB aa 360-508 / 508.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Human placenta tissue lysate, THP-1 cell lysate, HepG2, MCF-7, rat kidney tissue, human liver tissue, human placenta tissue, human pancreas tissue, mouse colon tissue, HepG2.