VEGFD Recombinant Rabbit Monoclonal Antibody [JE54-75]
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. Diseases associated with VEGFD include Anal Canal Squamous Cell Carcinoma and Kidney Angiomyolipoma. Among its related pathways are ERK Signaling and Ras signaling pathway. An important paralog of this gene is VEGFC.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
VEGFD
Swiss Prot
O43915 Human, P97946 Mouse, O35251 Rat
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human VEGFD aa 181-302 / 354.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Rat heart tissue lysate, NIH/3T3 cell lysate, HUVEC, rat kidney tissue, human small intestine tissue, mouse testis tissue, mouse heart tissue, A549.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200;FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 40 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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