Syntaxin 1a Recombinant Rabbit Monoclonal Antibody [JE54-37]
Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin-1A is a key protein in ion channel regulation and synaptic exocytosis.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
STX1A
Swiss Prot
Q16623 Human, O35526 Mouse, P32851 Rat
Cellular Locus
Cell membrane, synaptic vesicle membrane, synaptosome; Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Syntaxin 1a aa 1-50 / 288.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Mouse bone marrow tissue lysates, human cerebellum tissue lysates, rat brain tissue, human kidney tissue, human pancreas tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 33 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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