Calpain small subunit 1 Recombinant Rabbit Monoclonal Antibody [JE47-72]
Calpain small subunit 1 (CSS1), is a protein that in humans is encoded by the CAPNS1 gene. Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. The small regulatory subunit consists of an N-terminal domain, containing about 30% glycine residues and a C-terminal Ca-binding domain. Two transcript variants encoding the same protein have been identified for this gene.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CSS1, CANP small subunit, CDPS, CAPNS1, CAPN4, CAPNS
Swiss Prot
P04632 Human, O88456 Mouse, Q64537 Rat
Cellular Locus
Cytoplasm. Membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human Calpain small subunit 1 aa 1-140 / 268.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
A549 cell lysates, rat uterus tissue, human liver cancer tissue, human pancreas tissue, mouse liver tissue, mouse kidney tissue, A549.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 28 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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