TPPP Recombinant Rabbit Monoclonal Antibody [JE47-35]
Tubulin polymerization-promoting protein is a protein that in humans is encoded by the TPPP gene. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. This protein has been linked to multiple sclerosis myelin lesions and CSF abnormalities in multiple sclerosis patients. This has also been linked to Parkinson's and Alzheimer's Disease.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
TPPP, TPPP1
Swiss Prot
O94811 Human, Q7TQD2 Mouse, D3ZQL7 Rat
Cellular Locus
Cytoplasm. Cytoskeleton. Nucleus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human TPPP aa 80-185 / 219.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Mouse brain tissue lysates, rat brain tissue, human pancreas tissue, human uterus tissue, SHG-44.
Concentration
1 mg/mL
Dilution
WB:1:1,000-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 24 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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