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RNF40 Recombinant Rabbit Monoclonal Antibody [JE46-30]

E3 ubiquitin-protein ligase BRE1B is an enzyme that in humans is encoded by the RNF40 gene. The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

95 kDa retinoblastoma associated protein antibody 95 kDa retinoblastoma protein binding protein antibody 95 kDa retinoblastoma-associated protein antibody BRE 1B antibody BRE1 B antibody BRE1 E3 ubiquitin ligase homolog B antibody BRE1-B antibody BRE1B antibody BRE1B_HUMAN antibody DKFZp686K191 antibody E3 ubiquitin protein ligase BRE1B antibody E3 ubiquitin-protein ligase BRE1B antibody KIAA0661 antibody MGC13051 antibody Rb associated protein antibody RBP 95 antibody RBP95 antibody RING finger protein 40 antibody Ring finger protein 40 E3 ubiquitin protein ligase antibody RNF 40 antibody Rnf40 antibody STARING antibody

Abbreviation

BRE1-B, RBP95, RNF40, BRE1B, KIAA0661

Swiss Prot

O75150 Human, Q3U319 Mouse, Q8CJB9 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human RNF40 aa 211-451 / 1,001.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IP, IHC-P

Positive Control

HEK-293 cell lysate, HeLa cell lysate, C2C12 cell lysate, MEF cell lysate, Mouse testis tissue lysate, Rat testis tissue lysate, human colon tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IP: 1:10-1:50 ;IHC-P: 1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 114 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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