AP-A Recombinant Rabbit Monoclonal Antibody [JE46-03]
Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. ENPEP is considered to be an essential and highly specific enzyme, which metabolizes and inactivates bioactive peptides such as angiotensin II (AngII) in the renin-angiotensin system. ENPEP is expressed in neoplastic lesions of the uterine cervix, and its levels are upregulated as the lesions progress from cervical intraepithelial neoplasms to invasive squamous cell carcinomas. ENPEP expression is absent in normal cells and is overexpressed in cancer cell lines compared with normal cells of mammary origin.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
EAP, AP-A, CD249, ENPEP
Swiss Prot
Q07075 Human
Cellular Locus
Cell membrane, Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human AP-A aa 860-957 / 957.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human kidney tissue lysate, human small intestine tissue lysate, human kidney tissue, human small intestine tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:200-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 109 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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