FYB Recombinant Rabbit Monoclonal Antibody [JE44-80]
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
ADAP, p120/p130, FYB1, FYB, SLAP130
Swiss Prot
O15117 Human
Cellular Locus
Cell junction, Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human FYB aa 701-750 / 783.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
U937 cell lysate, Jurkat cell lysate, human tonsil tissue, human appendix tissue, human spleen tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 85 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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