KHSRP Recombinant Rabbit Monoclonal Antibody [JE41-64]

Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Far upstream element-binding protein 2 antibody FBP2 antibody FUBP2 antibody FUBP2_HUMAN antibody FUSE binding protein 2 antibody FUSE-binding protein 2 antibody KH type splicing regulatory protein (FUSE binding protein 2) antibody KH type splicing regulatory protein antibody KH type-splicing regulatory protein antibody KHSRP antibody KSRP antibody p75 antibody

Abbreviation

FUSE-binding protein 2, KSRP, KHSRP, FUBP2

Swiss Prot

Q92945 Human, Q3U0V1 Mouse, Q99PF5 Rat

Cellular Locus

Nucleus. Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human KHSRP aa 1-220 / 712.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP

Positive Control

293 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, 293T, LOVO, SH-SY5Y, rat testis tissue, human lung carcinoma tissue, human colon tissue, human kidney tissue, mouse brain tissue.