IMPDH2 Recombinant Rabbit Monoclonal Antibody [JE40-87]
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
IMP dehydrogenase 2, IMPD 2, IMPDH 2, IMPDH2, IMPD2
Swiss Prot
P12268 Human, P24547 Mouse, E9PU28 Rat
Cellular Locus
Nucleus. Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human IMPDH2 aa 80-320 / 514.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control
Daudi cell lysate, A431 cell lysate, A431, LOVO, PC-3M, rat kidney tissue, human tonsil tissue, human thyroid tissue, mouse testis tissue, Daudi.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:10-1:50 ;IP: 1:10-1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
56 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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