SUN1 Recombinant Rabbit Monoclonal Antibody [JG95-31]
UNC84A (UNC84 homolog A), also known as SUN1, is a multi-pass nuclear membrane protein that is involved in nuclear anchoring and migration. Highly expressed in heart, brain and testis, UNC84A functions as an A-type Lamin-binding protein that forms a link between the inner and outer nuclear envelope membranes. This link acts as a structural bridge between the nuclear interior and the Actin cytoskeleton and is essential for proper localization of nuclear envelope proteins. Additionally, UNC84A may be involved in telomere attachment and in normal testis development. UNC84A contains one UNC84 (SUN) domain and exists as four isoforms due to alternative splicing events.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
SUN1, KIAA0810, UNC84A
Swiss Prot
O94901 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Rat
Immunogen
Recombinant protein within Human SUN1 aa 90-240 / 812.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Rat kidney tissue lysates, A431, human breast tissue, human colon tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IHC-P: 1:50-1:200;IF-Cell: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
90 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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