EGR2 Recombinant Rabbit Monoclonal Antibody [JG78-39]
Selected Variant
ET7108-57
Size: 100 µL
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
EGR-2, EGR2, KROX20
Swiss Prot
P11161 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human EGR2 aa 2-96 / 476.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
SH-SY5Y cell lysate, HepG2 cell lysate, Daudi cell lysate, RAW264.7 cell lysate, PC-12 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
C1QA / Complement C1q A-Chain (C1QA/2955), 1mg/mL
IL3RA / CD123 (Acute Myeloid Leukemia Marker) (IL3RA/2065), CF488A conjugate, 0.1mg/mL
