Lipin 1 Recombinant Rabbit Monoclonal Antibody [JG37-69]
Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression (By similarity). Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity).
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
EC=3.1.3.4 antibody KIAA0188 antibody Lipin-1 antibody Lpin1 antibody LPIN1_HUMAN antibody PAP1 antibody Phosphatidate phosphatase LPIN1 antibody
Abbreviation
LPIN1
Swiss Prot
Q14693 Human
Cellular Locus
Nucleus. Cytoplasm. Endoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within Human Lipin 1 aa 81-220 / 890.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control
HUVEC, PC-3M, human liver carcinoma tissue, human colon tissue, human skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
98 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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