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USP9x Recombinant Rabbit Monoclonal Antibody [JG35-11]

Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Deubiquitinating enzyme FAF X antibody Deubiquitinating enzyme FAF-X antibody DFFRX antibody Drosophila fat facets related X linked antibody FAF antibody Fafl antibody Fam antibody Fat facets homolog antibody Fat facets in mammals antibody Fat facets protein related X linked antibody Fat facets protein related, X-linked antibody Fat facets protein-related antibody hFAM antibody MRX99 antibody Probable ubiquitin carboxyl terminal hydrolase FAF X antibody Probable ubiquitin carboxyl-terminal hydrolase FAF-X antibody Ubiquitin carboxyl-terminal hydrolase FAM antibody Ubiquitin specific peptidase 9 X linked antibody Ubiquitin specific peptidase 9, X-linked antibody Ubiquitin specific processing protease FAF X antibody Ubiquitin specific protease 9 X chromosome antibody Ubiquitin thioesterase FAF X antibody Ubiquitin thiolesterase FAF X antibody Ubiquitin thiolesterase FAF-X antibody Ubiquitin-specific protease 9 antibody Ubiquitin-specific-processing protease FAF-X antibody USP9 (gene name) antibody Usp9x antibody USP9X_HUMAN antibody Uubiquitin specific protease 9, X chromosome (fat facets like Drosophila) antibody X chromosome antibody X-linked antibody

Abbreviation

hFAM, USP9X, DFFRX, FAM, USP9

Swiss Prot

Q93008 Human, P70398 Mouse, D3ZC84 Rat

Cellular Locus

Cell projection, Cytoplasm, Cytoskeleton.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human USP9x aa 1-118 / 2,554.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

SiHa cell lysate, A549 cell lysate, 293 cell lysate, mouse colon tissue lysate, 293T, F9, SiHa, human tonsil tissue, mouse fallopian tube tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 290 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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