PARP2 Recombinant Rabbit Monoclonal Antibody [JG34-56]
Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
PARP-2, hPARP-2, ARTD2, ADPRT-2, pADPRT-2, PARP2, ADPRT2, ADPRTL2
Swiss Prot
Q9UGN5 Human
Cellular Locus
Chromosome, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human PARP2 aa 484-583 / 583.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HCT 116 cell lysate, HeLa cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 66 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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