eEF1A1 Recombinant Rabbit Monoclonal Antibody [JB44-13]

The elongation factor-1 complex is composed of two subunits, EF-1 α1 (elongation factor 1-alpha 1) and EF-1 α2 (elongation factor 1-alpha 2), and is responsible for the delivery of aminoacyl tRNAs to the ribosome. EF-1 α1 is expressed predominately in brain, placenta, lung, liver, kidney and pancreas, while EF-1 α2 is highly expressed in heart, brain and skeletal muscle. Both EF-1 α1 and α2 localize to the nucleus and belong to the GTP-binding elongation factor family. The gene encoding EF-1 α2, which maps to human chromosome 20q13.3, may play a role in the development of ovarian cancer, while the EF-1 α1 gene, mapping to chromosome 6Q14.1, is commonly present as an autoantigen in patients with Felty syndrome. Felty syndrome is a disorder characterized by rheumatoid arthritis, a swollen spleen, decreased white blood cell count, and increased susceptibility to infection.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

CCS 3 antibody CCS3 antibody Cervical cancer suppressor 3 antibody chunp6927 antibody CTCL tumor antigen antibody EE1A1 antibody EEF 1 antibody EEF1A antibody eEF1A-1 antibody EEF1A1 antibody EF-1-alpha-1 antibody EF-Tu antibody EF1A antibody EF1a like protein antibody EF1A1_HUMAN antibody Elongation factor 1 alpha subunit antibody Elongation factor 1-alpha 1 antibody Elongation factor Tu antibody Eukaryotic elongation factor 1 A-1 antibody Eukaryotic translation elongation factor 1 alpha 1 antibody Eukaryotic translation elongation factor 1 alpha 1 like 14 antibody Glucocorticoid receptor AF 1 specific elongation factor antibody GRAF 1EF antibody HNGC:16303 antibody ik:tdsubc_2a3 antibody ik:tdsubc_2b3 antibody LENG7 antibody Leukocyte receptor cluster (LRC) member 7 antibody Leukocyte receptor cluster member 7 antibody Prostate tumor inducing protein 1 antibody PTI1 antibody tdsubc_2a3 antibody Translation elongation factor 1 alpha 1 like 14 antibody wu:fa91c07 antibody wu:fa94b03 antibody wu:fi13b09 antibody xx:tdsubc_2a3 antibody xx:tdsubc_2b3 antibody

Abbreviation

EF-1-alpha-1, EF-Tu, eEF1A-1, EEF1A1, EEF1A, EF1A, LENG7

Swiss Prot

P68104 Human, P10126 Mouse, P62630 Rat

Cellular Locus

Cell membrane, Cytoplasm, Membrane, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human eEF1A1 aa 413-462 / 462.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC, IF-Cell, IF-Tissue

Positive Control

HeLa cell lysate, MCF7 cell lysate, 293T cell lysate, Jurkat cell lysate, HepG2 cell lysate, A431 cell lysate, THP-1 cell lysate, K-562 cell lysate, C2C12 cell lysate, Neuro-2a cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, C6 cell lysate, Rat kidney tissue lysate, human breast cancer tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue, HeLa, C2C12, PC-12.