CXCR5 Recombinant Rabbit Monoclonal Antibody [JB11-40]
Burkitt's lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G-protein coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer's patch follicles. BLC expression in Peyer's patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CXC-R5, CXCR-5, MDR-15, CXCR5, BLR1, MDR15
Swiss Prot
P32302 Human, Q04683 Mouse, P34997 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within C-terminal human CXCR5.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IF-Cell
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IF-Cell: 1:250
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 42 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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