DDAH2 Recombinant Rabbit Monoclonal Antibody [JB59-33]
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAH2, DDAH, G6A, NG30
Swiss Prot
O95865 Human, Q99LD8 Mouse, Q6MG60 Rat
Cellular Locus
Cytoplasm. Mitochondrion.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human DDAH2 aa 1-125 / 285.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IP
Positive Control
Rat heart tissue lysate, mouse heart tissue lysate, mouse lung tissue lysate, human lung tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IP: 1:10-:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 30 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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