Ctip1 Recombinant Rabbit Monoclonal Antibody [JB35-68]
The BCL11A gene encodes for a regulatory C2H2 type zinc-finger protein, that can bind to the DNA. Five alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been reported. The protein associates with the SWI/SNF complex, that regulates gene expression via chromatin remodelling. BCL11A is highly expressed in several hematopoietic lineages, and plays a role in the switch from γ- to β-globin expression during the fetal to adult erythropoiesis transition. Furthermore, BCL11A is expressed in the brain, where it forms a protein complex with CASK to regulate axon outgrowth and branching. In the neocortex, BCL11A binds to the TBR1 regulatory region and inhibits the expression of TBR1.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
BCL-11A, EVI-9, BCL11A, CTIP1, EVI9, KIAA1809, ZNF856
Swiss Prot
Q9H165 Human, Q9QYE3 Mouse
Cellular Locus
Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within Human Ctip1 aa 381-609 / 835.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IF-Cell, IF-Tissue
Positive Control
Jurkat cell lysates, Daudi cell lysate, Raji cell lysate, Jurkat, human lymph nodes tissue, mouse cerebellum tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IHC-P: 1:800 ;FC: 1:1,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 91 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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