SF3B1 Recombinant Rabbit Monoclonal Antibody [JB40-32]

Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Hsh 155 antibody MDS antibody Pre mRNA processing 10 antibody Pre mRNA splicing factor SF3b 155 kDa subunit antibody PRP 10 antibody PRP10 antibody PRPF 10 antibody PRPF10 antibody SAP 155 antibody SAP155 antibody SF3B 1 antibody SF3b155 antibody Spliceosome associated protein 155 antibody Splicing factor 3b subunit 1 155kDa antibody Splicing factor 3B subunit 1 antibody

Abbreviation

SF3b155, SAP 155, SF3B1, SAP155

Swiss Prot

O75533 Human, Q99NB9 Mouse

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human SF3B1 aa 1-105 / 1,304.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, IF-Tissue, FC

Positive Control

Mouse thymus tissue lysate, Hela cell lysate, rat brain tissue, human colon carcinoma tissue, human skin tissue, human kidney tissue, mouse small intestine tissue.