MMP-17 Recombinant Rabbit Monoclonal Antibody [JU33-03]
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
MMP-17, MT-MMP 4, MTMMP4, MT4-MMP, MT4MMP, MMP17, MT4MMP
Swiss Prot
Q9ULZ9 Human, Q9R0S3 Mouse
Cellular Locus
Secreted. Plasma membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human MMP17 aa 175-225 / 603.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Cell, IF-Tissue, IHC-P, WB
Positive Control
A549, MCF-7, mouse brain tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50 ;IHC-P: 1:50 ;WB: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
67 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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