ALDH1L1 Recombinant Rabbit Monoclonal Antibody [JU53-54]
10-formyltetrahydrofolate dehydrogenase is an enzyme that in humans is encoded by the ALDH1L1 gene. The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
10-FTHFDH, FDH, ALDH1L1, FTHFD
Swiss Prot
O75891 Human, Q8R0Y6 Mouse, P28037 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human ALDH1L1 aa 155-375 .
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue, IHC-Fr
Positive Control
A431, A549, LOVO, human liver tissue, human kidney tissue, mouse liver tissue, rat kidney tissue, rat brain tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-2,000 ;IHC-P: 1:200-1:1,000 ;IF-Tissue: 1:50-1:200 ;IHC-Fr: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 99 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
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