ACTL6A Recombinant Rabbit Monoclonal Antibody [JU40-32]

ACTL6A also named BAF53. The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

53 kDa BRG1 associated factor A antibody 53 kDa BRG1-associated factor A antibody ACL6A_HUMAN antibody Actin like 6A antibody Actin like protein 6A antibody Actin related protein 4 antibody Actin related protein antibody Actin related protein Baf53a antibody Actin-like protein 6A antibody Actin-related protein Baf53a antibody ACTL 6 antibody ACTL 6A antibody ACTL6 antibody ACTL6A antibody Arp4 antibody ARPN BETA antibody ArpNbeta antibody BAF 53A antibody BAF complex 53 kDa subunit antibody BAF53 antibody BAF53A antibody BRG1 associated factor antibody BRG1-associated factor 53A antibody hArpN beta antibody INO80 complex subunit K antibody INO80K antibody MGC5382 antibody

Abbreviation

BAF53A, ACTL6A, BAF53, BAF53A, INO80K

Swiss Prot

O96019 Human, Q9Z2N8 Mouse

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Recombinant protein within Human ACTL6A aa 185-326 .

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP

Positive Control

Jurkat cell lysates, mouse brain tissue lysates, LOVO, PC-3M, human spleen tissue, mouse brain tissue, mouse hippocampus tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:100 ;IF-Tissue: 1:50-1:100 ;IHC-P: 1:50-1:1,000 ;IP: 1:10-1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

47 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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